The year 1543 was remarkable in print-culture history. How's that for an understatement? Copernicus represents the revolutionary impulse to understand that which is outside of self (far outside), and Vesalius that which is inside of self (the body itself, so to speak).
Copernicus, "On the Revolultions of the Celestial Spheres"
Vesalius, "De Humani Corporis Fabrica"
Vesalius w/o Words
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